Weiss Lab @ PolyMTL

The Weiss Lab develops instruments and computational methods for single-molecule biophysics, super-resolution microscopy, and biological measurement.

WeissLab.ca Join the lab

Publications

Google Scholar Full list
2026 Single-Cell Probing of Nanoscale Bacterial Adhesion in Real-Time Using Optical Tweezers. Guillaume Ramadier, Sukanya Chakraborty, Inès Fonquernie, Tom Teiva Dessauvages, Caroline Boudoux, Yves V. Brun, Cecile Berne, Lucien Weiss ACS Nano, 2026; doi:10.1021/acsnano.6c03697 2026 Condition-dependent amorphous protein agglomerates control cytoplasmic rheology. José Losa, François Simon, Dmitrii Linnik, Saniye Gül Kaya, et al. Molecular Cell, 2026; doi:10.1016/j.molcel.2026.03.018 2026 Detecting directed motion and confinement in single-particle trajectories using hidden variables. François Simon, Guillaume Ramadier, Inès Fonquernie, Janka Zsok, et al. eLife, 2026; doi:10.7554/eLife.99347 2026 Patch deconvolution for Fourier light-field microscopy. Bin Fu, Caroline L. Jones, Daniel Heraghty, Shengbo Yang, et al. Biophysical Journal, 2026; doi:10.1016/j.bpj.2026.01.034 2025 Sticking to Green: Sustainable Solutions for Next-Generation Microelectronic Packaging with Plant-Derived and Bacterial Adhesives. Cecile Berne, Catherine Marsan-Loyer, Lucien Weiss, Yves Brun, David Danovitch, David Gendron, Serge Ecoffey ACS Sustainable Chemistry & Engineering, 2025; doi:10.1021/acssuschemeng.5c08258 2025 Large-scale visualization of alpha-synuclein oligomers in Parkinson's disease brain tissue. Rebecca Andrews, Bin Fu, Christina E. Toomey, Jonathan C. Breiter, et al. Nature Biomedical Engineering, 2025; doi:10.1038/s41551-025-01496-4 2025 High-throughput DNA repair monitoring in Saccharomyces cerevisiae suggests SSB- and DSB-induced chromatin reconfiguration. Yael Shalev Ezra, Alon Saguy, Gaia Levin, Lucien Weiss, Onit Alalouf, Yoav Shechtman Scientific Reports, 2025; doi:10.1038/s41598-025-17538-5 2024 A guide to single-particle tracking. Francois Simon, Lucien Weiss, Sven van Teeffelen Nature Reviews Methods Primers, 2024; doi:10.1038/s43586-024-00341-3

Preprints have not completed journal peer review.

2026 Mode-Selective Photonic Lanterns for Visible Wavelengths. Guillaume Ramadier, Rodrigo Itzamnà Becerra-Deana, Stephane Virally, Nicolas Godbout, Caroline Boudoux, Lucien Weiss Optica Open preprint, 2026; doi:10.1364/opticaopen.33038456 2026 Simultaneous plane illumination and detection in confocal microscopy using a mode-selective photonic lantern. Rodrigo Itzamná Becerra-Deana, Simon Desrochers, Raphaël Maltais-Tariant, Simon Brais-Brunet, et al. arXiv preprint, 2026; arXiv:2604.02494 2026 Local confinement within plasma membrane nanodomains promotes constitutive activity of GPCRs. Xiaohan Zhou, Maria Shemeteva, François Simon, Louis-Phillipe Picard, et al. bioRxiv preprint, 2026; doi:10.64898/2026.02.17.706370 2026 Analyzing single-molecule dynamics with both complex types of motion and complex transition kinetics: Benchmarking of ExaTrack. François Simon, Chris H. Wiggins, Lucien Weiss bioRxiv preprint, 2026; doi:10.64898/2026.01.22.700663 2025 α-Synuclein driven cell susceptibility in Parkinson’s disease. Jonathan C. Breiter, Joseph S. Beckwith, Emma E. Brock, Joanne Lachica, et al. bioRxiv preprint, 2025; doi:10.1101/2025.08.19.670819 2025 Fast analytical method to integrate multivariate Gaussians over hidden variables. Francois C. Simon, Justin Cardona, Sean Molesky, Lucien Weiss HAL preprint, 2025; hal-04692487v2

Citation counts from Crossref; checked .

2018 Deep-STORM: super-resolution single-molecule microscopy by deep learning. Elias Nehme, Lucien Weiss, Tomer Michaeli, Yoav Shechtman Optica, 2018; doi:10.1364/OPTICA.5.000458 609 Crossref citations 2020 DeepSTORM3D: dense 3D localization microscopy and PSF design by deep learning. Elias Nehme, Daniel Freedman, Racheli Gordon, Boris Ferdman, Lucien Weiss, et al. Nature Methods, 2020; doi:10.1038/s41592-020-0853-5 353 Crossref citations 2015 Precise three-dimensional scan-free multiple-particle tracking over large axial ranges with Tetrapod point spread functions. Yoav Shechtman, Lucien Weiss, Adam S. Backer, Steffen J. Sahl, W. E. Moerner Nano Letters, 2015; doi:10.1021/acs.nanolett.5b01396 286 Crossref citations 2019 Single-particle diffusion characterization by deep learning. N. Granik, Lucien Weiss, E. Nehme, M. Shalom, M. Chein, E. Perlson, Y. Roichman, Y. Shechtman Biophysical Journal, 2019; doi:10.1016/j.bpj.2019.06.015 195 Crossref citations 2016 Multicolour localization microscopy by point-spread-function engineering. Yoav Shechtman, Lucien Weiss, Adam S. Backer, Maurice Y. Lee, W. E. Moerner Nature Photonics, 2016; doi:10.1038/nphoton.2016.137 177 Crossref citations